The best spa hotels in Florida Keys

Hey! Indulge in the ultimate pampering experience at one of these luxurious spa hotels. Designed to provide relaxation, rejuvenation, and tranquility, these properties offer an array of wellness services that range from massages and facials to yoga classes and meditation sessions. To make your search for the perfect spa hotel in in Florida Keys easier, I've compiled this list of top-rated properties for your consideration. So sit back, relax, and explore your options - your ultimate wellness retreat awaits!

• 1 Playa Largo Resort & Spa, Autograph Collection Key Largo, United States

  

  Resort. Playa Largo Resort & Spa, Autograph Collection is set on 14.5 private bayfront acres in Key Largo, Florida. The resort features a year-round outdoor pool, private cabanas, a hot tub, fire pits, and water sport facilities. Each room boasts an interactive iPad and smart TV with cinema-effects for streaming movies and music. A dining table and seating area are included in each accommodation. The resort's La Marea restaurant has a variety of fresh vegetables and herbs grown in the property's seaside garden. The waterfront restaurant, Sol by the Sea, offers fresh seafood and a rum bar. The full-service Ocean Spa has skin and nail treatments, a salon, and fitness counseling and classes. Guests can even schedule an en suite massage. Views of the Florida Bay, a private marina, and a boat launch ramp are featured at the Playa Largo Resort. Paddle boards, kayaks, snorkeling, diving, boating, and ocean excursions are available on site. The resort is 4.3 km from Dolphins Plus Oceanside, where guests can swim with dolphins, and John Pennekamp Coral Reef State Park is 11 minutes' drive away. Show full description Guest review score 8.6, rooms from around $449.

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• 2 Hyatt Centric Key West Resort & Spa Key West, United States

  

  Resort. Stay in the heart of Key West. This waterfront resort features an on-site spa and fitness centre and is located on Key West Island. Guests can enjoy the nightlife and restaurants of Duval Street, which is only 3 minutes’ walk from the resort. A private balcony and free WiFi are included in every cosy room at the Hyatt Key West Resort and Spa. Additional amenities include a flat-screen cable TV and a small refrigerator. On-site Jala Spa offers a number of services, including body wraps, facials, and deep tissue massages. Nail care and renewal rituals are also available, as is an on-site fitness centre. An outdoor pool and hot tub offer the perfect space to rejuvenate while scuba diving, jet boats, and snorkeling are available on site or nearby. A Jet Ski island tour is available for guests looking to explore the surrounding area. Two on-site restaurants are located at Hyatt Key West Resort and Spa. Shor American Seafood Grill offers coastal fares while Blue Mojito Pool Bar and Grill serves cocktails and light bites. Show full description Guest review score 8.4, rooms from around $365.

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• 3 Ocean Key Resort & Spa, a Noble House Resort Key West, United States

  

  Resort. Stay in the heart of Key West. Lobby Renovations through February, 2026. Valued guests - We are excited to be redesigning our main entrance and adding a stunning new lobby with a bar and lounge that will overlook our marina. Work will be completed Monday to Saturday 8:30AM to 6:00PM. Our Restaurant, Spa, Pool and Sunset Pier will be operating as normal. Overlooking the Gulf of Mexico, this luxury Key West resort and spa features an outdoor pool with gulf views. Free WiFi is provided at Ocean Key Resort and Spa. On-site SpaTerre offers massage therapies, nail treatments, facials, and other spa services. The resort houses an on-site fitness centre and fishing boats, jet skis, and glass-bottom boat tours are available. From spa baths and private balconies offering partial and full ocean views, rooms and suites at Ocean Key Resort come well equipped. A coffee machine and a private bathroom are also featured. Enjoy dinner and dancing over the water at Sunset Pier or experience seafood paired with crafted cocktails at waterfront Hot Tin Roof. LIQUID Pool – Bar - Lounge serves cocktails and snacks. Mallory Square plaza is 1 minutes’ walk as are the restaurants, bars, and entertainment of Duval Street. Show full description Guest review score 8.4, rooms from around $1260.

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• 4 Pier House Resort & Spa Key West, United States

  

  Resort. Stay in the heart of Key West. Ideally set on a private beach in Key West's Old Town, Pier House Resort & Spa offers a full-service spa, instant beach access, and on-site dining. It is 1 minutes’ walk from Duval Street entertainment district. WiFi is complimentary, and every guest room features a small refrigerator, rain-style showers, and coffee and tea-making facilities. A flat-screen TV comes standard. Experience waterfront views from the outdoor pool or stay indoors and relax with massages and body rituals at the on-site spa. For added wellness, visit the on-site fitness centre. Savor fresh seafood and classic dishes for breakfast, lunch and dinner at the One Duval or sample cocktails near the seaside at Beach Bar. Two additional restaurants are on-site, including quirky Chart Room Bar. Nearby, adventure awaits via boat, parasailing, or Jet Ski. Hemingway Home and Museum is 5 minutes’ drive from Pier House Resort & Spa. Show full description Guest review score 8.3, rooms from around $1147.

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• 5 Isla Bella Beach Resort & Spa - Florida Keys Marathon, United States

  

  Resort. Situated in Marathon, within 7 km of Conch-Air Florida Keys Scenic Flights and 10 km of Florida Keys Aquarium Encounters, Isla Bella Beach Resort features a private beach area. Located around 6 km from Seven Mile Bridge, the resort is also 10 km away from Captain Hook s Marina Dive Center. A Deep Blue Dive Center is 11 km away. At the resort, rooms have a terrace. Rooms are fitted with a flat-screen TV, and certain units at Isla Bella Beach Resort have a balcony. The rooms feature a private bathroom with a bath. The property has a full breakfast menu to choose from. Our in-house restaurant serves a variety of Hawaiian Regional Cuisines. The wellness area at the accommodation is comprised of a hot tub and a fitness centre. Guests at Isla Bella Beach Resort will be able to enjoy activities in and around Marathon, like cycling and fishing. The resort also provides a business centre and guests can use the on-site ATM machine, check the newspapers or use the fax machine and photocopier at Isla Bella Beach Resort. Round-the-clock assistance is available at the reception. Dolphin Research Center is 19 km from the accommodation. The nearest airport is Florida Keys/Marathon International Airport, 8.1 km from Isla Bella Beach Resort. This property offers spa and wellness packages. Show full description Guest review score 8.8, rooms from around $948.

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• 6 The Gardens Hotel Key West, United States

  

  Hotel. Stay in the heart of Key West. Located in Key West, Florida, this adult-only hotel offers two outdoor pools. Duval Street is a 1-minute walk away, and Key West Butterfly and Nature Conservatory is 3 minutes’ drive from the hotel. A private balcony or patio with property views is provided in all rooms at The Gardens Hotel Key West. A flat-screen cable TV, ironing facilities, and a refrigerator are also featured in each room. Free Wi-Fi is available for guests. Guests can also take advantage of on-site bicycle hires, massage services, and concierge services. Live jazz music is performed in the gardens every Sunday evening as well for guests to enjoy. The Key West Shipwreck Museum, Key West Aquarium, and Conch Tour Train are all located less than 2 km away. The Ernest Hemingway Home and Museum is 500 m away from The Gardens Hotel. Guest review score 9.1, rooms from around $441.

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• 7 Hawks Cay Resort Marathon, United States

  

  Resort. Featuring a full-service spa, this resort hotel has five pools, including an adults-only pool, a children's pool, tennis courts, and pickleball courts. Fishing, diving, and jet skiing are offered in the clear waters of Hawks Cay. Spa services include massages, body bar treatments, and facials. Salon services are also available, and the property houses a fitness centre, complete with cardio and strength training machines. Island-themed rooms and cottages feature Caribbean-style wood furniture. A flat-screen cable TV, refrigerator and coffee maker are provided. Free WiFi is available. There are 5 onsite dining options, including Salt + Ash by Michelin-starred chef Jeremy Ford, Angler & Ale, Pilar Bar, Tiki Bar, and The Cafe, which serves breakfast as well as all day grab and go bites and beverages. The Hawks Cay Resort is a half-mile from Duck Key Marina. Curry Hammock State Park is 17 minutes away. Show full description Guest review score 7.3, rooms from around $785.

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• 8 Baker's Cay Resort Key Largo, Curio Collection By Hilton Key Largo, United States

  

  Resort. Situated on the Gulf of Mexico and surrounded by lush landscaping and nature trails, Baker's Cay Resort Key Largo, Curio Collection By Hilton offers private beach access. Each guestroom comes standard with a small refrigerator, coffee maker, and ironing facilities. A TV, complete with premium cable and in-room movies, is provided. Select rooms feature a balcony. A variety of water sports, including snorkeling, diving, and boat tours are also available at the resort. Guests can also enjoy 2 outdoor swimming pools as well as a modern on-site fitness center. The Baker's Cay Resort Key Largo, Curio Collection By Hilton is 11 minutes' drive from John Pennekamp National Marine Sanctuary. Theater of the Sea marine animal park is 21 minutes' drive away. This property offers spa and wellness packages. Show full description Guest review score 8.0, rooms from around $957.

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I try my best to keep this guide up to date and I last refreshed it in December 2022. Did I miss a spa hotel that should be on this list? Send me an email and let me know!