The best spa hotels in Rochester

Hey! Indulge in the ultimate pampering experience at one of these luxurious spa hotels. Designed to provide relaxation, rejuvenation, and tranquility, these properties offer an array of wellness services that range from massages and facials to yoga classes and meditation sessions. To make your search for the perfect spa hotel in in Rochester easier, I've compiled this list of top-rated properties for your consideration. So sit back, relax, and explore your options - your ultimate wellness retreat awaits!

• 1 Hilton Rochester Mayo Clinic Area Rochester, United States

  

  Hotel. Set 400 metres from Plummer Building, Hilton Rochester Mayo Clinic Area offers 4-star accommodation in Rochester and has a shared lounge, a terrace and a bar. Offering a restaurant, the property also has a fitness centre, as well as a sauna and a hot tub. The hotel offers an indoor pool and room service. At the hotel, all rooms include a desk, a TV, a private bathroom, bed linen and towels. All guest rooms at Hilton Rochester Mayo Clinic Area feature air conditioning and a safety deposit box. Guests at the accommodation can enjoy an American breakfast. The property has a hairdresser's and business centre. Staff at Hilton Rochester Mayo Clinic Area are available to provide information at the 24-hour front desk. Mayo Civic Center is 400 metres from the hotel, while Charlton Building Heliport is 1.4 km from the property. The nearest airport is Rochester International Airport, 13 km from Hilton Rochester Mayo Clinic Area. Show full description Guest review score 8.8, rooms from around $263.

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I try my best to keep this guide up to date and I last refreshed it in December 2025. Did I miss a spa hotel that should be on this list? Send me an email and let me know!