The best spa hotels in Rochester

Hey! Indulge in the ultimate pampering experience at one of these luxurious spa hotels. Designed to provide relaxation, rejuvenation, and tranquility, these properties offer an array of wellness services that range from massages and facials to yoga classes and meditation sessions. To make your search for the perfect spa hotel in in Rochester easier, I've compiled this list of top-rated properties for your consideration. So sit back, relax, and explore your options - your ultimate wellness retreat awaits!

• 1 Hilton Rochester Mayo Clinic Area Rochester, United States

  

  Hotel. Set 400 metres from Plummer Building, Hilton Rochester Mayo Clinic Area offers 4-star accommodation in Rochester and has a shared lounge, a terrace and a bar. Offering a restaurant, the property also has a fitness centre, as well as a sauna and a hot tub. The hotel features an indoor pool and room service. At the hotel, all rooms include a desk. Complete with a private bathroom fitted with free toiletries, all guest rooms at Hilton Rochester Mayo Clinic Area have a flat-screen TV and air conditioning, and certain rooms also offer a seating area. All rooms will provide guests with a fridge. The property has a hairdresser's and business centre. The accommodation can conveniently provide information at the reception to help guests to get around the area. Mayo Civic Center is 400 metres from Hilton Rochester Mayo Clinic Area. Rochester International Airport is 13 km from the property. Show full description Guest review score 8.6, rooms from around $235.

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I try my best to keep this guide up to date and I last refreshed it in August 2026. Did I miss a spa hotel that should be on this list? Send me an email and let me know!